最近の業績


1.原著論文

1) Sugiyama A, Hata S, Suzuki K, Yoshida E, Nakano R, Mitra S, Arashida R, Asayama Y, yabuta  Y and Takeuchi T: Oral administration of paramylon, a β-1,3-D-glucan isolated from Euglena gracilis Z inhibits development of atopic dermatitis-like skin lesions in NC/Nga mice. J. Vet. Med. Sci., 72: 755-763, 2010.

2) Sugiyama A, Sato A, Shimizu H, Ando K, Takeuchi T: PEGylated lactoferrin enhances its hepatoprotective effects on acute liver injury induced by D-galactosamine and lipopolysaccharide in rats. J. Vet. Med. Sci., 72: 173-180, 2010.

3) Nojima Y, Suzuki Y, Yoshida K, Abe F, Shiga T, Takeuchi T, Sugiyama A, Shimizu H and Sato A: Lactoferrin conjugated with 40-kDa branchedpoly (ethylene glycol) has an improved circulating half-life. Pharmaceutical Res., 26: 2125-2132, 2009.

4) Sugiyama A, Sato A and Takeuchi T: PEGylated lactoferrin enhanced its hepatoprotective effects on acute liver injury induced by carbon tetrachloride in rats. Food and Chemical Toxicology, 47: 1453-1458, 2009.

5) Sugiyama A, Suzuki K, Mitra S, Arashida R, Yoshida E, Nakano R, Yabuta Y and Takeuchi T: Hepatoprotective effects of paramylon, a β-1,3-D-glucan isolated from Euglena gracilis Z on acute liver injury induced by carbon tetrachloride in rats. J. Vet. Med. Sci., 71: 885-890, 2009.

6) Komiya M, Sugiyama A, Tanabe K, Uchino T and Takeuchi T: Evaluation of the effect of topical application of lavender oil on autonomic nerve activity in dogs. Am. J. Vet. Med. Res., 70: 764-769, 2009.

7) Matuu A, Hashizume T, Kanda T, Nagano M, Sugiyama A, Okamoto Y and Hikasa Y: A case of persistent mullerian duct syndrome with sertoli cell tumor and hydrometra in a dog. J. Vet. Med. Sci., 71: 379-381, 2009.

8) Nojima Y, Suzuki Y, Iguchi K, Shiga T, Fujimoto T, Yoshida K, Shimizu H, Takeuchi T and Sato A: Development of poly (ethylene glycol) conjugated lactoferrin for oral administration. Bioconjugate Chem., 19: 2253-2259, 2008.

9) Sugiyama A, Takeuchi T, Morita T, Matsuu A, Kanda T, Shimada A, Amaya T and Hikasa Y: Mediastinal lymphoma with complete atrioventricular block in a horse. J. Vet. Med. Sci., 70: 1101-1105, 2008.


10) Sugiyama A, Morita T, Shimada A, Tsuka T, Okamoto Y and Takeuchi T: Primary Malignant Peripheral nerve sheath tumor with eosinophilic cytoplasmic globules arising from the greater omentum in a dog. J. Vet. Med. Sci., 70: 739-742, 2008.

11) Kanemori N, Takeuchi T, Sugiyama A, Miyabayashi M, Kitagawa H, Shimizu H, Ando K and Harada E. Trans-endothelial and trans-epithelial transfer of lactoferrin into the brain through BBB and BCSFB in adult rats. J. Vet. Med. Sci., 70: 313-315, 2008.

12) Matsuu A, Kanda T, Sugiyama A, Murase T and Hikasa Y: Mitral stenosis with bacterial myocarditis in a cat. J. Vet. Med. Sci., 69: 1171-1174, 2007.

13) Sugiyama A, Takeuchi T, Morita T, Okamura Y, Minami S, Tsuka T, Tabuchi T and Okamoto Y: Lymphangiosarcoma in a cat. J. Comp. Path., 137: 174-178, 2007.

14) Sugiyama A, Ozaki K, Miyazaki Y, Tanabe Y, Takeuchi T and Narama I: Renal dysplasia unrelated to Claudin-16 deficiency in Japanese Black Cattle. J. Comp. Path., 137: 71-77, 2007.

15) Sugiyama A, Ozaki K, Takeuchi T and Narama I: Cardiac vascular hamartoma in two slaughtered cattle. J.Comp. Path., 136: 202-205, 2007.

16) Takeuchi T, Jyonotsuka T, Kamemori N, Kawano G, Shimizu H, Ando K and Harada E: Enteric-formulated lactoferrin was more effectively transported into blood circulation from gastrointestinal tract in adult rats. Exp. Physiol., 91: 1033-1040, 2006.

17) Komiya M, Takeuchi T and Harada E: Lemon oil vapor causes an anti-stress effect via modulating the 5-HT and DA activities in mice. Behav. Brain Res., 172: 240-249, 2006.

18) Tsuchiya T, Takeuchi T, Hayashida K, Shimizu H, Ando K and Harada E: Milk-derived lactoferrin may block tolerance to morphine analgesia. Brain Res.,1068: 102-108, 2006.

19) 杉山晶彦: クロディーン16欠損遺伝子保因ヘテロの黒毛和種牛に認められた腎尿細管形成不全症の1例. 日獣会誌, 59: 57-60, 2006.

20) Morita T, Takahashi M, Takeuchi T, Hikasa Y, Ikeda S, Sawada M, Sato K, Shibahara T, Shimada A: Changes in extracellular neurotransmitters in the cerebrum of familial idiopathic epileptic Shetland sheepdogs using an intracerebral microdialysis technique and immunohistochemical study for glutamate metabolism. J. Vet. Med. Sci., 67: 1119-1126, 2005.
 
      
21) Ishikado A, Imanaka H, Takeuchi T, Harada E and Makino T: Liposomalization of lactoferrin enhanced it's anti-inflammatory effects via oral administration. Biol. Pharm. Bull., 28: 1717-1721, 2005.

22) 杉山晶彦: 豚の巣状分節性腎異形成症の1例. 日獣会誌, 58: 347-349, 2005.


23) 杉山晶彦: と畜解体されたクロディーン16欠損症の黒毛和種牛6例の腎臓病変. 日獣会誌, 58: 763-767, 2005.

24) Sugiyama A, Ozaki K and Narama I: Diffuse global granulomatous glomerulonephritis in a pig. J. Vet. Med. Sci., 67: 87-90, 2005.

25) Kanemori N, Takeuchi T, Hayashida K and Harada E: Suppressive effects of milk-derived lactoferrin on psychological stress in adult rats. Brain Res., 1029: 34-40, 2004.

26) Takeuchi T, Kitagawa H and Harada E: Evidence of lactoferrin transportation into blood circulation from intestine via lymphatic pathway in adult rats. Exp. Physiol., 89: 263-270, 2004.

27) Takeuchi T, Shimizu H, Ando K and Harada E: Bovine lactoferrin reduces plasma triacylglycerol and NEFA accompanied by decreased hepatic cholesterol and triacylglycerol contents in rodents. Br. J. Nutr., 91: 533-538, 2004.

28) Hayashida K, Kaneko T, Takeuchi T, Shimizu H, Ando K and Harada E: Oral administration of lactoferrin inhibits inflammation and nociception in rat adjuvant-induced arthritis. J. Vet. Med. Sci., 66: 149-154, 2004.

29) Hayashida K, Takeuchi T and Harada E: Lactoferrin enhances peripheral opioid-mediated antinociception via nitric oxide in rats. Eur. J. Pharmacol., 484: 175-181, 2004.

30) Hayashida K, Takeuchi T, Ozaki T, Shimizu H, Ando K, Miyamoto A and Harada E: Bovine lactoferrin has a nitric oxide-dependent hypotensive effect in rats. Am. J. Physiol., 286: R359-R365, 2004.

31) 杉山晶彦: 59ヵ月齢の黒毛和種牛に認められた腎異形成症の1例. 日獣会誌, 57: 813-816, 2004.

32) 杉山晶彦: 豚の卵巣血管過誤腫の1例. 日獣会誌, 57: 531-533, 2004.

33) 杉山晶彦: 豚に認めた肝細胞胆管細胞混合型腺腫の2例. 日獣会誌, 57: 58-61, 2004.

34) Harada E, Shizuyama M, Ihara N and Takeuchi T: Impaired pancreatic endocrine and exocrine responses in growth-retarded piglets. J. Vet. Med. A, 50: 433-441, 2003.

35) Talukder MJR, Takeuchi T and Harada E: Receptor-mediated transport of lactoferrin into the cerebrospinal fluid via plasma in young calves. J. Vet. Med. Sci., 65: 957-964, 2003.

36) Hayashida K, Takeuchi T, Shimizu H, Ando K and Harada E: Lactoferrin enhances opioid-mediated analgesia via nitric oxide in the rat spinal cord. Am. J. Physiol., 285: R306-R312, 2003.

37) Takeuchi T, Hayashida K, Inagaki H, Kuwahara M, Tsubone H and Harada E: Opioid mediated suppressive effect of milk-derived lactoferrin on distress induced by maternal separation in rat pups. Brain Res., 979: 216-224, 2003.

38) Kitagawa H, Yoshizawa Y, Yokoyama T, Takeuchi T, Talukder MJR, Shimizu H, Ando K and Harada E: Persorption of bovine lactoferrin from the intestinal lumen into the systemic circulation via the portal vein and the mesenteric lymphatics in growing pigs. J. Vet. Med. Sci., 65: 567-572, 2003.

39) Talukder MJR, Takeuchi T and Harada E: Characteristics of lactoferrin receptor in bovine intestine: higher binding activity to the epithelium overlying Peyer's patches. J. Vet. Med. A, 50: 123-131, 2003.

40) Takeuchi T, Aletta JM, Laychock SG, Tian Y and Rubin RP: Role of nerve growth factor in the regulation of parotid cell differentiation induced by rat serum. Biochem. Pharmacol., 65: 1507-1513, 2003.

41) Hayashida K, Takeuchi T, Shimizu H, Ando K and Harada E: Novel function of bovine milk-derived lactoferrin on antinociception mediated by μ-opioid recepter in the rat spinal cord. Brain Res., 965: 239-245, 2003.

42) Takeuchi T, Iwanaga M and Harada E: Possible regulatory mechanism of DHA-induced anti-stress reaction in rats. Brain Res., 964: 136-143, 2003.

43) Sugiyama A, Ozaki K and Narama I: Deformed liver with prominent proliferation of bile ducts in a pig. J. Vet. Med. Sci.,65: 655-658, 2003.

44) Takeuchi T and Harada E: Age-related changes in sleep-wake rhythm in dog. Behav. Brain Res., 136: 193-199, 2002.

45) Harada E, Araki Y, Furumura E, Takeuchi T, Sitizyo K, Yajima T and Kuwata T: Characteristic transfer of colostrum-derived biologically active substances into cerebrospinal fluid via blood in natural suckling neonatal pigs. J. Vet. Med. A, 49: 358-364, 2002.

46) Morita T, Shimada A, Yashiro S, Takeuchi T, Hikasa Y, Okamoto Y and Mabuchi Y:  Myofiber expression of class Ⅰ major histocompatibility complex accompanied by CD8⁺ T-cell-associated myofiber injury in a case of canine polymyositis. Vet. Pathol., 39: 512-515, 2002.

47) Talukder MJR, Takeuchi T and Harada E: Transport of colostral macromolecules into the cerebrospinal fluid via plasma in newborn calves. J. Dairy Sci., 85: 514-524, 2002.

48) Morita T, Shimada A, Takeuchi T, Hikasa Y, Sawada M, Ohiwa S, Takahashi M, Kudo N, Shibahara T, Miyata H and Ohama E: Cliniconeuropathologic findings of familial frontal lobe epilepsy in Shetland sheepdogs. Can. J. Vet. Res., 66: 35-41, 2002.

49) Takeuchi T, Fukumoto Y and Harada E: Influence of a dietary n-3 fatty acid deficiency on the cerebral catecholamine contents, EEG and learning ability in rat. Behav. Brain Res.,131: 193-203, 2002.

50) 岡田光司, 日笠喜朗, 佐藤耕太, 籠田勝基, 森田剛仁, 島田章則, 竹内 崇, 前田豊之: 黒毛和種牛における後頭骨形成異常を伴う先天性内水頭症の1例. 日獣会誌, 54: 767-771, 2001.
 

2.著書

1) 竹内 崇: ストレス百科事典,ISBN: 978-4-621-08111-2,うつ病とストレス(n-3 および n-6脂肪酸の役割),p.166-180,ストレス百科事典翻訳刊行委員会編,丸善,東京,2009.

2) 竹内 崇,杉山晶彦: 実験で学ぶ生理学,ISBN: 978-4-87362-162-3,Chapter 2 血液に関する実験,pp.15-22,獣医生理学・生化学教育懇談会編,学窓社,東京,2009.